2024-2025 Academic Catalog
Welcome to Virginia Tech! We are excited that you are here planning your time as a Hokie.
Welcome to Virginia Tech! We are excited that you are here planning your time as a Hokie.
The Chemistry Department offers four undergraduate programs: the B.S. in Chemistry, the B.S. in Medicinal Chemistry, the B.S. in Polymer Chemistry, and the B.A. in Chemistry. The B.S. in Chemistry curriculum provides the breadth and depth to give graduates a wide choice of career options, including further graduate studies. The Chemistry Department is accredited by the American Chemical Society's Committee on Professional Training and the B.S. Chemistry degree meets the guidelines for an ACS-certified degree. The B.S. in Medicinal Chemistry prepares students for enrollment in health professional schools or for careers in the pharmaceutical industry. The B.S. in Polymer Chemistry has a concentration in the area of polymer and material sciences. The B.A. program has fewer required chemistry courses, allowing students to design a chemistry program with more electives to meet a wider set of career goals. The B.A. is often chosen by students who wish to pursue a double major or to take other courses to prepare for professional school, law, or business. Any of the degrees are suitable to prepare for high school teaching. The Chemistry Department supports and encourages all chemistry majors to pursue undergraduate research sometime during their degree program.
The Department offers M.S. and Ph.D. degrees with specializations in many areas of chemistry. (See the Graduate Catalog for further information.)
The requirements to earn a minor in Chemistry can be found on the specific checksheet by visiting the University Registrar website at http://registrar.vt.edu/graduation-multi-brief/index1.html.
University policy requires that students who are making satisfactory progress toward a degree meet minimum criteria toward the General Education (Pathways to General Education) (see "Academics") and toward the degree.
Satisfactory progress requirements toward the B.A. and B.S. in Chemistry, the B.S. in Medicinal Chemistry, and the B.S. in Polymer Chemistry can be found on the major checksheet by visiting the University Registrar website at http://registrar.vt.edu/graduation-multi-brief/index1.html.
Chair: A. J. Morris
Associate Chair: J. B. Matson
University Distinguished Professor: T. D. Crawford
Ethyl Corporation Chaired Professor: T. D. Crawford
Professors: D. Troya7, H. C. Dorn, A. R. Esker, F. A. Etzkorn L. A. Madsen, J. B Matson, J. S. Merola3,7, R. B. Moore, A. J. Morris, J. R. Morris, W. L. Santos, J. M. Tanko, and E. F. Valeev
Associate Professors: P. A. Deck, F. Lin, G. G. Liu, G. L. Long3, N. Mayhall, B. M. Tissue, and G. T. Yee7
Assistant Professors: A. Figg, E. C. Gentry, D. Iovan, A. Lowell, E. Mevers, L. Quan, M. Schulz, V. V. Welborn, and J. C. Worch
Research Associate Professor: C. Slebodnick
Senior Instructors: S. M. Arachchige, M. A. Berg, M. B. Bump and J. E. Eddleton3,4
Advanced Instructor: V. K. Long
Instructors: A. Geller, N. J. McAlpine, K. Neidigh, E. B. Orler, C. Santos, A. Wagner, and C. Wall4
Assistant Professor of Practice: T. R. Saarinen
Director of Graduate Programs: A. R. Esker
Graduate Program Coordinator: J. Huynh
Director of Undergraduate Programs: P. A. Deck
Undergraduate Program Coordinator: A. Kokkinakos
Director of General Chemistry: S. M. Arachchige
Orientation to the Chemistry Department and to the discipline of chemistry for chemistry majors and for individuals considering CHEM as a major, including transfer students. Resources for success, both generally as a college student and specifically as a chemistry major. Opportunities for mentoring, individual research and community involvement across the university and within the Chemistry Department. Exploration of career pathways for chemistry majors. Interconnections among professional practice, disciplinary progress, accepted standards for ethical use of information, principles of diversity and inclusion, and individual or personal value systems. Scientific communication, professional networking, and chemistry in the public eye.
Mathematical problem solving skills required for success in general chemistry. Manipulation of symbolic algebraic formulas. Dimensional analysis and narrative mathematical exercises. Application of problem solving techniques to chemical processes and reactions. Generation and interpretation of graphs using computer software. Elementary features of atoms, molecules, and the periodic table of the elements. Molar quantities, chemical nomenclature, reaction stoichiometry, and introductory solution chemistry.
Survey of chemistry across areas of specialization for students enrolled in curricula other than science and engineering. History and fundamental concepts and theories of chemistry, including the consequences of changes in parameters on chemical systems. Impact of chemistry in the context of areas of public concern and policy, including best practices for sustainability, rational decision-making, ethical use of scientific information, product and process stewardship. Chemistry as a basis for decision-making in the context of individual values and beliefs, and the roles of values and beliefs in the progress of chemistry as a human endeavor. The foregoing to be based on the concepts of chemistry as follows: 1015: Periodicity and atomic structure; nuclear chemistry; chemical bonding and reactivity; organic chemistry, polymer chemistry, and medicinal chemistry. 1016: Chemical stoichiometry including conservation of matter and energy; acid-base and oxidation-reduction chemistry of solutions; stoichiometry and thermodynamics, agricultural and environmental chemistry, chemistry of household and personal care products
Survey of chemistry across areas of specialization for students enrolled in curricula other than science and engineering. History and fundamental concepts and theories of chemistry, including the consequences of changes in parameters on chemical systems. Impact of chemistry in the context of areas of public concern and policy, including best practices for sustainability, rational decision-making, ethical use of scientific information, product and process stewardship. Chemistry as a basis for decision-making in the context of individual values and beliefs, and the roles of values and beliefs in the progress of chemistry as a human endeavor. The foregoing to be based on the concepts of chemistry as follows: 1015: Periodicity and atomic structure; nuclear chemistry; chemical bonding and reactivity; organic chemistry, polymer chemistry, and medicinal chemistry. 1016: Chemical stoichiometry including conservation of matter and energy; acid-base and oxidation-reduction chemistry of solutions; stoichiometry and thermodynamics, agricultural and environmental chemistry, chemistry of household and personal care products
Virtual laboratory exercises and reading and writing assignments designed to accompany 1015 and 1016, as applicable. Illustrates and elaborates on principles addressed in lecture, including history and fundamental concepts, theories, contexts, with an emphasis on sustainability issues and ethical consequences of decision- making in chemistry. Students will identify foundational concepts in chemistry, enumerate parameters likely to influence the outcome of an experiment, analyze the ways that values and beliefs influence progress in the discipline and communicate chemical concepts to a lay audience.
Virtual laboratory exercises and reading and writing assignments designed to accompany 1015 and 1016, as applicable. Illustrates and elaborates on principles addressed in lecture, including history and fundamental concepts, theories, contexts, with an emphasis on sustainability issues and ethical consequences of decision- making in chemistry. Students will identify foundational concepts in chemistry, enumerate parameters likely to influence the outcome of an experiment, analyze the ways that values and beliefs influence progress in the discipline and communicate chemical concepts to a lay audience.
A companion course for students needing supplemental help with mathematical and problem-solving skills required for CHEM 1035 General Chemistry. Manipulation of algebraic formulas. Application of problem-solving techniques to chemical processes and reactions. Quantitative methods applied to unit conversions, reaction yields, energy of reactions, and gas properties. Examination of atomic structure, periodicity, and molecular bonding. May not count towards degree requirements; consult advisor. Pass/Fail only.
First chemistry course for students in science curricula. Applications of reasoning in the natural sciences using chemical laws in an applied context and in the student’s own discipline. Overview of the universal aspects of chemistry and of application of chemistry to address global challenges. 1035: Problem-solving, elements and periodic table, stoichiometry of chemical reactions, gas phase of matter, energy flow and chemical change, atomic structure, and theories of chemical bonding. 1036: Properties of the three states of matter alone and in mixtures, kinetics, aqueous equilibrium, thermodynamics, electrochemistry. (Duplicates 1015-1016.) Students may bypass prerequisites for 1035 through testing alternatives listed in the Registrar’s Timetable.
First chemistry course for students in science curricula. Applications of reasoning in the natural sciences using chemical laws in an applied context and in the student’s own discipline. Overview of the universal aspects of chemistry and of application of chemistry to address global challenges. 1035: Problem-solving, elements and periodic table, stoichiometry of chemical reactions, gas phase of matter, energy flow and chemical change, atomic structure, and theories of chemical bonding. 1036: Properties of the three states of matter alone and in mixtures, kinetics, aqueous equilibrium, thermodynamics, electrochemistry. (Duplicates 1015-1016.) Students may bypass prerequisites for 1035 through testing alternatives listed in the Registrar’s Timetable.
Hands-on, real-world activities that illustrate and elaborate on concepts taught in general chemistry lecture (1035-1036), including acids and bases, heat capacity, ideal gases, states of matter, concentration, mixtures, energy flow and spontaneity in processes, equilibrium, kinetics, colligative properties, and electrochemistry. Use of instrumentation to analyze water and soil contaminants, biofuel mixtures, nanoparticles, and polymer properties. Laboratory safety, chemical hygiene, hazard mitigation, waste management, and the influence of procedure on experimental outcomes. Global challenges, including recycling and sustainable energy sources, water resource management, global warming, and environmentally friendly reagents in chemical contexts. Use of computers in data analysis, collaboration, and report-writing.
Hands-on, real-world activities that illustrate and elaborate on concepts taught in general chemistry lecture (1035-1036), including acids and bases, heat capacity, ideal gases, states of matter, concentration, mixtures, energy flow and spontaneity in processes, equilibrium, kinetics, colligative properties, and electrochemistry. Use of instrumentation to analyze water and soil contaminants, biofuel mixtures, nanoparticles, and polymer properties. Laboratory safety, chemical hygiene, hazard mitigation, waste management, and the influence of procedure on experimental outcomes. Global challenges, including recycling and sustainable energy sources, water resource management, global warming, and environmentally friendly reagents in chemical contexts. Use of computers in data analysis, collaboration, and report-writing.
In depth treatment of chemical bonding, thermodynamics, chemical equilibrium, reaction kinetics, descriptive chemistry of the elements, acid-base chemistry, chemistry of gases, liquids and solids, and other topics. This class is restricted to chemistry and biochemistry majors. Other students may request consent of instructor.
In depth treatment of chemical bonding, thermodynamics, chemical equilibrium, reaction kinetics, descriptive chemistry of the elements, acid-base chemistry, chemistry of gases, liquids and solids, and other topics. This class is restricted to chemistry and biochemistry majors. Other students may request consent of instructor.
Accompanies 1055-1056. Selected experiments illustrate principles taught in lecture. This class is restricted to chemistry and biochemistry majors. Other students may request consent of instructor.
Accompanies 1055-1056. Selected experiments illustrate principles taught in lecture. This class is restricted to chemistry and biochemistry majors. Other students may request consent of instructor.
A first course in analytical chemistry. Topics covered include volumetric and gravimetric analysis, and elementary spectroscopy.
Practical introduction to wet methods of quantitative chemical analysis based on fundamental chemical principles. Prior credit for OR concurrent registration of 2114 lecture is required for 2124 lab.
A one-semester course in analytical chemistry emphasizing the principles of equilibrium with examples from acid-base, complexation, solubility, and redox chemistry. The course also introduces the principles of spectroscopic, electrochemical, and chromatographic instrumentation.
A one-semester laboratory course in analytical chemistry that provides practical training in wet chemical methods, atomic and molecular spectroscopy, electrochemistry, and separations.
Application of fundamental principles in a systematic study of bonding and reactivity of the elements and their compounds.
Short course in fundamentals of organic chemistry with emphasis on nomenclature, isomerism, and properties of organic compounds. Compounds of importance to biology and biochemistry stressed. (Prior credit for 2535 precludes credit for this course.) One year of Chemistry required.
Structure, stereochemistry, reactions, and synthesis of organic compounds.
Structure, stereochemistry, reactions, and synthesis of organic compounds. Pre: One year of chemistry, including lab.
The laboratory accompanies lectures in organic chemistry 2535 and 2536.
The laboratory accompanies lectures in organic chemistry 2535 and 2536.
Synthesis and characterization of organic compounds using modern laboratory techniques.
Synthesis and characterization of organic compounds using modern laboratory techniques.
Writing organic reaction mechanisms; rationalizing and predicting organic reaction outcomes; selecting reagents for organic reactions; designing syntheses of several elementary steps; visualizing molecular stereochemistry.
Organic chemistry for chemistry majors. Structure and reactions of organic compounds, with emphasis on fundamental principles, theories, synthesis, and reaction mechanisms. The subject matter partially duplicates that of 2535-2536; no credit will be given for the duplicated courses.
Organic chemistry for chemistry majors. Structure and reactions of organic compounds, with emphasis on fundamental principles, theories, synthesis, and reaction mechanisms. The subject matter partially duplicates that of 2535-2536; no credit will be given for the duplicated courses.
Honors section.
Exploration and development of post-baccalaureate career options, including non-traditional options, for chemistry students. Opportunities in the government, private and academic sectors. Career planning. Managing application processes for graduate school, professional school, and employment. Development of materials (resumes, cover letters, portfolios, and personal statements) needed for applications. Fellowships and scholarships for graduate study. Opportunities for career-relevant experience before graduation. Integrity in career development. Open to majors in Chemistry, Medicinal Chemistry, and Polymer Chemistry.
Chemistry and global impacts of postconsumer materials including trash, biodegradable, recyclable, and reusable materials. Waste management of metals, ceramics, and polymers in the context of their chemical properties. Reliability and accuracy of information sources on postconsumer materials. Complex contemporary issues involving disposal and repurposing of postconsumer materials including health impacts, energy, cost, water quality, return value, and environmental and cultural considerations.
Principles of thermodynamics, kinetics, and quantum mechanics applied to chemical equilibria, reactivity, and structure. Partly duplicates 4615, cannot receive credit for both 3615 and 4615.
Principles of thermodynamics, kinetics, and quantum mechanics applied to chemical equilibria, reactivity, and structure. Partly duplicates 4616, cannot receive credit for both 3616 and 4616.
Laboratory study of selected physico-chemical principles and methods. Data acquisition, data analysis, and report writing are stressed.
Laboratory study of selected physico-chemical principles and methods. Data acquisition, data analysis, and report writing are stressed. I
Organization of quantum information (assemblies of bits) for quantum-computing applications in chemistry, physics, biology, and computer science. Numerical methods for quantum software, emphasizing spin lattices and simulations such as quantum games. Best practices for programming, including techniques for quantum-coding (in Python or Julia), structuring a software product for quantum-computational science use, version control, and cloud-based documentation and code-sharing (via Github). Classical/quantum translation.
Application of academic knowledge and skills to in a work-based experience aligned with post-graduation goals using research-based learning processes. Satisfactory completion of work-based experience often in the form of internship, undergraduate research, co-op, or study abroad; self-evaluation; reflection; and showcase of learning. Pre: Departmental approval of 3900 plan.
Use of the chemical literature as an aid to professional activities. Pre: Junior Major Standing.
A senior-level laboratory course that integrates previous laboratory and lecture experiences to illustrate the interconnectedness of the curriculum leading to the BA in Chemistry. Modern experimental methods and instrumentation, including chromatographic separations, nuclear magnetic resonance, infrared spectrometry, and mass spectrometry. Independent experimental design and execution of an experimental synthetic reaction in chemistry, including scaling, selection of reagents and solvents, and development of a procedure for completing the reaction, isolating the product, and characterizing it for structure and bulk purity. Best practices in lab safety, chemical hygiene, note-keeping, and professional report-writing. Principles of green chemistry. Pre: Senior standing.
Experimental techniques used in the synthesis of various linear polymers, copolymers, and crosslinked networks. Determination of polymer molecular weights and molecular weight distribution. Methods used in the thermal, mechanical, and morphological characterization of polymeric systems.
Principles of instrumental methods including data analysis, phase equilibrium, spectroscopy, and electrochemistry. Applications of modern instrumentation to chemical analyses using chromatography, electrophoresis, atomic and molecular spectroscopy, potentiometry, and voltammetry. Note: Graduate students will not be expected to take the corequisite lab 4124.
Hands-on experience with modern instrumental methods of analysis. Experiments use spectroscopy, electrochemistry, and separations.
A study of spectroscopic, bonding, and structural properties of inorganic compounds.
Synthesis and characterization of inorganic compounds using modern laboratory techniques.
Structure, properties, and applications of natural polysaccharides. Natural sources and methods of isolation. Synthetic chemistry and important polysaccharide derivatives. Relation of structure and properties to performance in critical applications including pharmaceuticals, coatings, plastics, rheology control, and films. Conversion by chemical and biochemical methods of polysaccharide biomass to fuels and materials.
Synthesis, structure, properties, and reactivity patterns of main-group and transitionmetal organometallic compounds. Applications of organometallic compounds in chemical synthesis and catalysis.
Principles underpinning the study of metal ions in biological systems. Review of basic coordination chemistry. Evolution of the distribution of metal ions in biology. Uptake of metal ions from the environment into living organisms. Regulation of metal ion concentrations in cells. Central functions of metal ions in biological systems including modulation of structure, electron transfer reactions, substrate binding and activation, and selective transfer of atoms and groups. Roles of biopolymers in the binding, regulation, and function of metal ions. Physical methods of analysis relevant to bioinorganic chemical research questions. Senior standing.
Sustainability, waste prevention, conservation of energy resources, avoidance of toxins, pollutants, and hazards in chemical processes and products. Life-cycle analysis applied to case studies involving process development and product stewardship. Applications in chemical industry, process and product design, and public policy.
Structure determination of organic compounds by spectroscopic methods. Interpretation of 1H and 13C nuclear magnetic resonance (NMR) spectra including two-dimensional (2D) spectra. Mass spectrometric (MS) techniques including tandem MS. Selection and application of minor organic-analytical techniques for structure elucidation. Formatting of spectroscopic data for publication. Course credit will not be awarded for both CHEM 4524 and CHEM 5524G.
Structure, synthesis, and basic characteristics of the major classes of polymerization reactions including step-growth (condensation) and chain growth (addition), free radical, and ionic mechanisms.
Laboratory experience tracing a standard pathway that potential drug targets follow in many medicinal chemistry laboratories. Synthesis of potential drug compounds and verification of their purity and structural identity primarily using mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. Optimization of conditions for a biochemical assay and verification of its reproducibility. Use of an optimized assay to measure the potency of potential drug compounds to achieve a desired biochemical effect. Application of structure-activity relationships to propose new chemical structures that might show further improvements in potency. Best practices in laboratory safety, chemical hygiene, note-keeping, and professional report-writing. Senior standing.
Structure, synthesis, and physiological effects of major classes of pharmaceutical agents including CNS depressants and stimulants, analgesics, anesthetics, cardiovascular agents, chemotherapeutic drugs, and oral contraceptives.
The organic chemistry underlying the structure and properties of amino acids, peptides, and nucleic acids. Mechanisms of enzyme catalysis and coenzyme-mediated reactions. Mechanisms and thermodynamics of catabolism and anabolism of fats, carbohydrates, and proteins, and of other key biological reactions. Principles of solid-phase synthesis applied to peptides and nucleic acids. Biosynthesis of lipids, sugars, and terpenoids.
Principles of thermodynamics, chemical kinetics, and chemical bonding for students in the life sciences. 4615: Laws and applications of thermodynamics. 4616: Chemical kinetics and chemical bonding including spectroscopy. Partly duplicates 3615, cannot receive credit for 3615 and 4615.
Principles of thermodynamics, chemical kinetics, and chemical bonding for students in the life sciences. 4615: Laws and applications of thermodynamics. 4616: Chemical kinetics and chemical bonding including spectroscopy. Partly duplicates 3616, cannot receive credit for both 3616 and 4616.
Fundamental principles of solid-state materials chemistry in energy sciences. Thermodynamics and kinetics of electron and ion transport in solid materials. Application of electrochemical and photochemical principles to batteries, fuel cells, solar cells, and other energy devices. Analytical tools and characterization methods for elucidating mechanisms within electrochemical and photoelectrochemical cells, with an emphasis on using electrochemical principles to evaluate battery chemistry. Solid-liquid interfacial mechanisms in energy devices. Critical analysis of relevant primary literature. Formulation of hypotheses and experimental design for improving device performance. Pre: Senior standing.
Physical chemical fundamentals of polymers and surfaces including adhesives and sealants.
Modern software collaboration techniques and tools including collaborative code repositories and cloud-based documentation. Application of structure and version control to software and documentation. Developing code with industry-standard quantum-software modules. Hands-on scientific coding for quantum problems. Project management skills including proposal development and technical presentation delivery.
Chemistry of inorganic and organic soil components with emphasis on environmental significance of soil solution-solid phase equilibria, sorption phenomena, ion exchange processes, reaction kinetics, redox reactions, and acidity and salinity processes.
Honors section.
Honors section.
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